Combinations ; See Below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Indivir | Hetero Drugs Ltd | Unisel Pharma (K) Ltd. | 400mg | 180 | Tablet | per tablet | KES 3,322.00 |
| Indinavir More info | |
|---|---|
| Mode Of Action | Protease inhibitors (PI) Inhibits HIV proteases, preventing viral maturation and replication |
| Drug Indication | HIV infection in combination with other ARVs. |
| Precautions | Monitoring of aminotranferases, bilirubin level, cholesterol and triglycerides, on bi-monthly basis; increased risk of nephrolithiasis in case of dehydration; reduce dose in case of marked liver impairment; blood concentration is reduced in the 3rd trimester of pregnancy. |
| Contra-Indications | Acute porphyria, hypersensitivity reactions, alprazolam, alfuzosin, amiodarone, rifampicin and sildenafil. |
| Side Effects | Common side effect is nephrolithiasis (kidney stones) which is more likely in children; unconjugated hyperbilirubinaemia; malaise; flank pain; back pain; abdominal pain; alopecia; ingrown toe nails; dried cracked skin (retinoid syndrome); vasculitis; oedema; haemolytic anaemia and hepatitis. |
| Dosage | 800mg orally TID |
| Pregnancy Category | Category B3 |
| Pregnancy Category Description | Drugs which have been taken by only a small number of pregnant women and women of child-bearing age with no any established rise in the frequency of malformations or other direct or indirect detrimental effects on the foetus having been noted. Studies in animals show evidence of an increased occurrence of foetal damage, the significance of which is uncertain in human |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Hiv Chemotherapy |